They are far from satisfactory for most patients and some of these have limitations to their use.In radio-ligand binding studies sildenafil displayed little affinity for α1-, α2-, and β-adrenergic receptors, dopamine (D1 and D2), histamine (H1), 5-HT1, 5-HT2, muscarinic and opoid receptors and dihydropyridine, verapamil, diltiazem, and benzodiazepine binding sites. cialis.

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